Hesperidin Methyl Chalcone

Hesperidin Methyl Chalcone (HMC) is an effective source of water-soluble flavonoids, with applications as versatile as nutraceuticals, cosmetics and beverages.

  • Molecular Formula: C29H36O15
  • Molecular Weight: 624.59 g/mol
  • CAS No.: 24292-52-2
  • Character: Light yellow crystalline powder, slight smell, slight bitter taste, soluble in water and ethanol.

Applications / Uses:

  • HMC has blood vessel-stabilizing & -strengthening effects. It protects capillaries and small veins so they are less likely to leak fluid into the surrounding tissue. HMC supports and protects the integrity of the vascular system with particular activity in the capillaries and veins. It has been shown to help strengthen capillaries by increasing capillary resistance and decreasing capillary permeability. It also results in increased venous motility, tone, and vessel dilation.
  • One study showed that HMC, in combination with other ingredients, reduced leg tightness and swelling in people with chronic venous insufficiency and varicose veins. There is also some evidence that taking HMC as a dietary supplement reduces hot flashes in women going through menopause.
  • Due to its antioxidant activity, HMC is also a widely used ingredient in the cosmetic industry, used in formulating anti-aging products like anti-aging night creams, moisturizers, sunscreens and body lotions. Antioxidants help to protect skin cells against free radicals produced by exposure to sunlight and pollutants in the environment. Hence, they are also used for products to reduce dark circles under the eyes.
  • There has also been considerable research showing benefits of HMC in oral supplements.
  • HMC is also used as a raw material for drugs for lowering cholesterol, anti-virus and anti-inflammatory.

Hesperidin methyl chalcone is widely used in South-Africa, USA, EU, not only in pharmaceutical but also in dietary supplement and cosmetic products.

Specifications: Not less than 98%